For developers and power users, ( winusb.sys ) is a generic driver provided by Microsoft that allows user-mode applications to communicate with USB devices without writing a custom kernel-mode driver.

It supports common data transfer types like bulk, control, interrupt, and (starting with Windows 8.1) isochronous transfers.

Support the WinUSB API as a backend. · Issue #209 · pyusb ... - GitHub

Zadig is a popular third-party GUI tool used to quickly swap a device's current driver for the WinUSB driver, which is often required for libraries like libusb or PyUSB to work on Windows.