Vampires typically interact with magic in one of two ways: they are either highly resistant or uniquely vulnerable to specific forms.

Victims who survive a bite in some systems may become dizzy and hostile or fall under a hypnotic charm that makes them regard the vampire as a "trusted friend". The Ultimate Guide to Vampirism

Biting another vampire is sometimes used as a quick way to heal immediate injuries. Combat Utility:

In the World of Darkness system, a vampire drinking the blood of another vampire is called Diablerie. This act can devour the target's soul, granting the attacker significant power or increasing their "generation" (power cap).

The effect of a bite varies depending on the victim's status and the vampire's intent.

There is a rare rule where a resurrection or similar spell cast on a vampire can actually "rebound" and strike the caster if the vampire successfully resists it. The Mechanics of a Vampire Bite

Games like Vampyr use the bite as a tactical move; stunning an enemy allows a vampire to bite them to replenish their own Blood Bar , which is then used to fuel magical abilities.

In some classic guides, vampires can use standard magic items but suffer double damage if they touch items attuned to "non-evil" persons or specific holy professions.