Transferases are found throughout the cell, with high concentrations in the cytosol, mitochondria, and Golgi bodies. Molecule of the Month: Glutathione Transferases - PDB-101
), critical for DNA methylation and gene expression regulation.
A−X+B→A+B−Xcap A minus cap X plus cap B right arrow cap A plus cap B minus cap X is the donor, is the functional group, and is the acceptor. Primary Subclasses
) between an amino acid and a keto acid, playing a key role in amino acid metabolism. : Transfer methyl groups ( −CH3negative cap C cap H sub 3
A transferase is an enzyme that catalyzes the transfer of a specific functional group (such as a methyl or phosphate group) from a donor molecule to an acceptor molecule. These enzymes are vital for metabolic pathways, including the synthesis and degradation of carbohydrates, proteins, lipids, and nucleic acids. Core Mechanism and Classification