: Virtually 0% five-year survival without treatment.
: Without treatment, approximately 63% of early gastric cancers will progress to advanced disease within five years. The median time for a tumor to grow from an early stage to an advanced stage is estimated at 34 months. Stomach Cancer Prognosis Without Treatment
: The doubling time for stomach cancer tumors varies by stage; it is approximately 11.8 months for T1 tumors and 6.2 months for T4 tumors. Life Expectancy and Survival Statistics : Virtually 0% five-year survival without treatment
The "natural history" of untreated stomach cancer describes how the disease advances through the body if no medical intervention occurs: : The doubling time for stomach cancer tumors
: Metastasis (spread) occurs in 80–90% of individuals with untreated stomach cancer. Once it reaches Stage IV (distant metastasis), survival rates drop to almost nil. Progression of Symptoms
: Progression time between stages shortens as the disease becomes more aggressive. While it may take 34 months to move between Stage I and II, the progression from Stage III to IV can take as little as 1.8 months.
The prognosis for stomach cancer without treatment is generally poor, with the disease typically progressing to advanced stages that lead to death for the majority of patients. Untreated stomach cancer has a stomach cancer 5-year survival rate that drops significantly from 46.2% at stage I to 0% for stages II, III, and IV. The Natural History and Progression