After testing positive for the BRCA1 gene mutation , she opted for a bilateral (double) mastectomy to significantly reduce the risk of recurrence. Advocacy:

The two have appeared together to promote Breast Cancer Awareness Month, notably on a special 2006 episode of , where they shared preventive tips and supported hair donations for cancer patients. The Ellen DeGeneres Show - Aired Order - All Seasons

Sheryl Crow was diagnosed with breast cancer in February 2006 at the age of 44.