The episode revolves around a chaotic series of events triggered by William Shatner's scheduled appearance on Hilary's talk show.
William Shatner guest stars as himself, delivering a memorable performance as a legendary actor under the influence of dental medication.
Will and Carlton try to manage the situation and get a loopy Shatner onto the stage for the live taping. The result is a bizarre interview where Shatner’s dental anesthesia makes for a hilarious, albeit unprofessional, appearance on Hilary's show.