Pearlcam

Researchers use PearlCAM to test new "smart" dyes that attach specifically to cancer cells. By viewing the animal through the Pearl system, surgeons can practice identifying tumor margins that would be invisible to the naked eye. Washington University has utilized this for foundations in translational imaging. 2. Drug Delivery Tracking

By tagging medications (such as encapsulated liposomes) with fluorescent markers, scientists can monitor how long a drug stays in the bloodstream and whether it successfully reaches the tumor site. This is critical for improving the efficiency of chemotherapy. 3. Longitudinal Tumor Studies

Capabilities typically include 700 nm and 800 nm channels, allowing researchers to track two different biological markers simultaneously. 📈 Key Applications in Research

The software quantifies the signal intensity, allowing researchers to say exactly how much of a drug reached the target compared to healthy tissue. 🌟 Why It Matters

A fluorescent probe (like IRDye®) is injected into the subject.

High-sensitivity detection of signals from within internal organs or deep-seated tumors.

The system is a staple in laboratories focusing on translational medicine. Key use cases include: 1. Fluorescence-Guided Surgery

Because the imaging is non-invasive, researchers can scan the same animal over days or weeks. This reduces the number of animals needed for a study and provides a more accurate timeline of how a tumor grows or shrinks in response to treatment. 🛠 Features and Workflow