: The 49ers' defense limited Falcons QB Michael Penix Jr. to one touchdown and forced a fumble.
The San Francisco 49ers and Atlanta Falcons share a deep-rooted history, having met since 1966 . Once fierce division rivals in the NFC West , they now face off as cross-divisional foes after the Falcons moved to the NFC South in 2002. Mon, Oct 20 49ers won! Recent Matchup (October 19, 2025) NFL San Francisco 49ers Vs Atlanta Falcons
Falcons vs. 49ers: A look at the series history going into 2025 : The 49ers' defense limited Falcons QB Michael Penix Jr
: The teams have split two postseason meetings ( 1–1 ). Once fierce division rivals in the NFC West
: Christian McCaffrey dominated with 129 rushing yards and two touchdowns .
: The loss dropped Atlanta to a 3–3 record , while the 49ers secured a critical conference win. All-Time Series & Rivalry The 49ers hold the upper hand in this long-standing series: Series Record : San Francisco leads 49–33–1 .
While the 49ers lead the all-time series, recent years have been more competitive, with Atlanta winning three of the last five meetings.