Explain what the results mean for the broader field (e.g., therapeutic targets for neurodegenerative diseases).

Establish the importance of the field (e.g., mitochondrial quality control in neurons). Problem Statement: Identify the gap your paper addresses.

Clear and descriptive (e.g., "The Impact of [Variant Name] on Transcellular Mitophagy in [Cell Type]" ).

Glaucoma-associated Optineurin mutations increase ... - eLife

Use clear figures and charts to show the variant's behavior.