Rar — Hem#265

This paper highlights a novel method that combines the ligand-binding domain (LBD) of RAR with the trafficking machinery of the GR, creating a chimeric receptor that moves from the cytoplasm to the nucleus upon ligand binding. 2. Methodology: Design of the GR-RAR Chimera

The chimeric receptor provides a dramatic and easily monitored visual indicator of RAR ligand presence in the cellular environment. Hem#265 rar

Are you looking to focus on the of RAR or the technical design of the chimera? This paper highlights a novel method that combines