Akari Yamazaki Now

A significant portion of her co-authored work focuses on the apolipoprotein E (APOE) gene—specifically the ε4 allele, which is the strongest genetic risk factor for Alzheimer's disease.

: Her research published in journals like Arteriosclerosis, Thrombosis, and Vascular Biology has demonstrated that ApoE in Brain Pericytes regulates endothelial cell phenotype. This showed that ApoE4 impairs the basement membrane formation of capillaries, contributing to cognitive decline. akari yamazaki

Yamazaki's chemical research frequently focuses on and related fused-ring systems. Azulene is known for its deep blue color and unusual dipole moment, making its derivatives highly sought after for advanced materials and pharmaceuticals. A significant portion of her co-authored work focuses

: She contributed to vital studies in Nature Neuroscience evaluating how liver-expressed (peripheral) apoE4 compromises synaptic plasticity and exacerbates brain amyloid pathology. ⚗️ Focus 2: Akari Yamazaki in Organic Chemistry ⚗️ Focus 2: Akari Yamazaki in Organic Chemistry