A Change Is Gonna Comegrey's Anatomy : Season 4... Apr 2026

The hospital is flooded with casualties from a three-car accident. Notable cases include a man who has suffered an "internal decapitation"—his head is held to his body only by skin and muscle—and a pregnant woman whose severed arm Meredith must locate.

The episode picks up seventeen days after the Season 3 finale. Meredith, Cristina, Izzie, and Alex are now with interns of their own to mentor—a task they find as daunting as it is exciting. A Change Is Gonna ComeGrey's Anatomy : Season 4...

Among the new interns is Lexie Grey (played by Chyler Leigh), Meredith’s half-sister whom she has never met, and George O'Malley , who is forced to repeat his intern year after failing his exams. The hospital is flooded with casualties from a

A New Era at Seattle Grace: "A Change Is Gonna Come" The Season 4 premiere of Grey's Anatomy , titled serves as a pivotal "reboot" for the series. Airing originally on September 27, 2007, it transitions the core cast from interns to residents, fundamentally shifting the power dynamics at Seattle Grace Hospital. Plot Summary: Residents, Interns, and a Deer Meredith, Cristina, Izzie, and Alex are now with

In one of the show's more unusual storylines, Izzie Stevens risks her professional reputation by attempting to save a dying deer brought in by a young boy, much to the confusion of her new interns. Core Themes and Character Shifts